TxMLKM-021 (P03170) Protein Card

General Information
Name TxMLKM-021
Alternative name(s) Tx3-Q01
Organism Conus textile (Cloth-of-gold cone)
Organism region Indo-Pacific
Organism diet molluscivorous
Protein Type Wild type
Protein precursor TxMLKM-021 precursor (631)
TxMLKM-021 precursor (4741)
TxMLKM-021 precursor (4742)
Notes There is an ambiguity for position 11, which could be occupied by an isoleucine or a leucine.

Classification
Conopeptide class conotoxin
Gene superfamily M superfamily
Cysteine framework III
Pharmacological family

Sequence
VCCPFGGCHELCQCCE(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Sequence evidence protein level
Average Mass 1723.99
Monoisotopic Mass 1722.55
Isoelectric Point 4.50
Extinction Coefficient [280nm] NA

References
Ueberheide,B.M., Fenyö,D., Alewood,P.F. and Chait,B.T. (2009) Rapid sensitive analysis of cysteine rich peptide venom components. Proc. Natl. Acad. Sci. U.S.A. 106:6910-6915
Bhatia,S., Kil,Y.J., Ueberheide,B., Chait,B.T., Tayo,L., Cruz,L., Lu,B., Yates,J.R. 3rd. and Bern,M. (2012) Constrained de novo sequencing of conotoxins. J. Proteome Res. 11:4191-4200
Dobson,R., Collodoro,M., Gilles,N., Turtoi,A., De Pauw,E. and Quinton,L. (2012) Secretion and maturation of conotoxins in the venom ducts of Conus textile. Toxicon 60:1370-1379

Internal links
Protein Precursor TxMLKM-021 precursor (631)
TxMLKM-021 precursor (4741)
TxMLKM-021 precursor (4742)
Nucleic acids
Structure

External links

Tools