SxIIIB (P03585) Protein Card

General Information

Name	SxIIIB
Alternative name(s)	StIIIB,Sx3B
Organism	Conus striolatus
Organism region	Indo-Pacific
Organism diet	piscivorous
Protein Type	Wild type
Notes	The superfamily assignment is not supported by any available data but the cDNA extraction method is based on the conservation of the signal sequence.

Classification

Conopeptide class	conotoxin
Gene superfamily	M superfamily
Cysteine framework	III
Pharmacological family	mu conotoxin

Sequence

ZKCCTGKKGSCSGRACKNLRCCA(nh2)
Modified residues	position symbol name 1 Z Pyroglutamic acid 24 nh2 C-term amidation
Sequence evidence	nucleic acid level
Average Mass	2381.82
Monoisotopic Mass	2380.02
Isoelectric Point	NA
Extinction Coefficient [280nm]	NA

References

Walewska A, Skalicky JJ, Davis DR, Zhang MM, Lopez-Vera E, Watkins M, Han TS, Yoshikami D, Olivera BM, Bulaj G (2008) NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA J Am Chem Soc 130:14280-14286

Internal links

Nucleic acids
Structure

External links

UniProtKB/Swiss-Prot	P0C8V3
Ncbi	P0C8V3

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Thursday 28 September 2023