Sr1.1 (P03902) Protein Card

General Information

Name	Sr1.1
Alternative name(s)	SrIB [γ15>E]
Organism	synthetic construct
Protein Type	Synthetic
Parent	SrIA

Classification

Conopeptide class	conotoxin
Gene superfamily
Cysteine framework	I
Pharmacological family	alpha conotoxin

Sequence

RTCCSROTCRMEYPELCG(nh2)
Modified residues	position symbol name 7 O 4-Hydroxyproline 19 nh2 C-term amidation
Sequence evidence	Unknown
Average Mass	2116.44
Monoisotopic Mass	2114.86
Isoelectric Point	10.50
Extinction Coefficient [280nm]	1490.00

References

López-Vera,E., Aguilar,M.B., Schiavon,E., Marinzi,C., Ortiz,E., Restano Cassulini,R., Batista,C.V., Possani,L.D., Heimer de la Cotera,E.P., Peri,F., Becerril,B. and Wanke,E. (2007) Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors. FEBS J. 274:3972-3985

Internal links

Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 21 March 2023