AuIA (P00404) Protein Card

General Information

Name	AuIA
Alternative name(s)	Au1a
Organism	Conus aulicus
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Wild type
Protein precursor	AuIA precursor (2878)

Classification

Conopeptide class	conotoxin
Gene superfamily	A superfamily
Cysteine framework	I
Pharmacological family	alpha conotoxin

Sequence

GCCSYPPCFATNSDYC(nh2)
Modified residues	position symbol name 17 nh2 C-term amidation
Sequence evidence	protein level
Average Mass	1725.89
Monoisotopic Mass	1724.57
Isoelectric Point	2.19
Extinction Coefficient [280nm]	2980.00

References

Luo,S., Kulak,J.M., Cartier,G.E., Jacobsen,R.B., Yoshikami,D., Olivera,B.M. and McIntosh,J.M. (1998) alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release J. Neurosci. 18:8571-8579

Internal links

Protein Precursor	AuIA precursor (2878)
Nucleic acids
Structure

External links

UniProtKB/Swiss-Prot	P56639
Ncbi	P56639

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Monday 5 June 2023