Tx2 precursor (P00053) Protein Card

General Information

Name	Tx2 precursor
Organism	Conus textile (Cloth-of-gold cone)
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Precursor
Notes	The mature peptide regions is from Lu BS et al. 1999, the only reference, and differs from the Swiss-Prot card.

Classification

Conopeptide class	conotoxin
Gene superfamily	A superfamily
Pharmacological family

Sequence

MGMRMMFTVFLLVVLATTVVS FTSGRRTFHGRNAAAKASGL VSLTDRR PECCSHPACNVDHPEICR
Sequence region	[1-21] signal sequence [49-66] mature peptide Tx2

References

Lu,B.S., Yu,F., Zhao,D., Huang,P.T. and Huang,C.F. (1999) Conopeptides from Conus striatus and Conus textile by cDNA cloning Peptides 20:1139-1144

Internal links

Nucleic acids	Alpha-conotoxin peptides Conus textile alpha A conotoxin Tx2 precursor, mRNA, complete cds
Structure

External links

UniProtKB/Swiss-Prot	Q9XZK7
Ncbi	Q9XZK7, AAD31913

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Wednesday 6 December 2023