Conantokin-Rl2 precursor (P05849) Protein Card

General Information

Name	Conantokin-Rl2 precursor (named by ConoServer)
Organism	Conus rolani
Protein Type	Precursor

Classification

Conopeptide class	conantokin
Gene superfamily	B1 superfamily
Pharmacological family

Sequence

MQLYTYLYLLVPLVTFHLILG TGTLDHGDALTERRSTDATA LKPEPVLLQKSSARSTNDNGKDTQMKRILKKRGNKAR GEEE LAEKAPEFARELAN
Sequence region	[1-21] signal sequence [79-96] mature peptide Conantokin-Rl2

References

Gowd,K.H., Han,T.S., Twede,V., Gajewiak,J., Smith,M.D., Watkins,M., Platt,R.J., Toledo,G., White,H.S., Olivera,B.M. and Bulaj,G. (2012) Conantokins derived from the Asprella clade impart conRl-B, an N-methyl d-aspartate receptor antagonist with a unique selectivity profile for NR2B subunits. Biochemistry 51:4685-4692

Internal links

Nucleic acids
Structure

External links

UniProtKB/Swiss-Prot	P0DKZ0
Ncbi	P0DKZ0

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 26 September 2023