TxIXA precursor (P00608) Protein Card

General Information

Name	TxIXA precursor
Organism	Conus textile (Cloth-of-gold cone)
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Precursor

Classification

Conopeptide class	conotoxin
Gene superfamily	P superfamily
Pharmacological family

Sequence

MHLSLARSAVLMLLLLFALGNFVVVQS GQITRDVDNGQLTD NRRNLQSKWKPVSLYMSRR GCNNSCQEHSDCESHCICTFRG CGAVN G
Sequence region	[1-27] signal sequence [61-87] mature peptide TxIXA

References

Miles,L.A., Dy,C.Y., Nielsen,J., Barnham,K.J., Hinds,M.G., Olivera,B.M., Bulaj,G. and Norton,R.S. (2002) Structure of a Novel P-superfamily Spasmodic Conotoxin Reveals an Inhibitory Cystine Knot Motif J. Biol. Chem. 277:43033-43040

Lirazan,M.B., Hooper,D., Corpuz,G.P., Ramilo,C.A., Bandyopadhyay,P., Cruz,L.J. and Olivera,B.M. (2000) The spasmodic peptide defines a new conotoxin superfamily Biochemistry 39:1583-1588

Internal links

Nucleic acids	Conus textile P superfamily conotoxin Tx9a precursor, gene, complete cds.
Structure

External links

UniProtKB/Swiss-Prot	Q9GU58
Ncbi	Q9GU58, AAG28406

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 21 March 2023