Conorphin-T precursor (P06097) Protein Card

General Information

Name	Conorphin-T precursor (named by ConoServer)
Alternative name(s)	Tx5.15 precursor
Organism	Conus textile (Cloth-of-gold cone)
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Precursor

Classification

Conopeptide class	conotoxin
Gene superfamily	T superfamily
Pharmacological family

Sequence

MRCLPVIVILLLLIASAPSVDA QPKTKDDIPQASFLDNAKR YLQVLESKR NCCRRQICC GRNH
Sequence region	[1-22] signal sequence [51-59] mature peptide Conorphin-T[bead] [51-59] mature peptide Conorphin-T[ribbon] [51-59] mature peptide Conorphin-T[globular]

References

Brust,A., Croker,D.E., Colless,B., Ragnarsson,L., Andersson,A., Jain,K., Garcia-Caraballo,S., Castro,J., Brierley,S.M., Alewood,P.F., Lewis,R.J. (2016) Conopeptide-Derived κ-Opioid Agonists (Conorphins): Potent, Selective, and Metabolic Stable Dynorphin A Mimetics with Antinociceptive Properties J Med Chem

Internal links

Nucleic acids	Conus textile T superfamily conotoxin Tx5.15 precursor, mRNA, complete cds.
Structure

External links

Ncbi

AGK23221

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 28 March 2023