FrVIA precursor (P06807) Protein Card

General Information

Name	FrVIA precursor
Organism	Conus frigidus
Protein Type	Precursor
Notes	Homologous to SuVIA mature peptide. Likely has an essential role for prey capture or defence (Jin et al., 2015).

Classification

Conopeptide class	conotoxin
Gene superfamily	O1 superfamily
Cysteine framework	VI/VII
Pharmacological family

Sequence

MKLTCILAVGLLFLTAWTFVTA DDSTGSENRGLWETLFPKA RDEVENPEGDEVKKR DCHESGDFCGIPGVKNGLCCSQSCWV VCTPEW
Sequence evidence	nucleic acid level
Sequence region	[1-22] signal sequence [57-88] mature peptide FrVIA

References

Jin,A.H., Israel,M.R., Inserra,M.C., Smith,J.J., Lewis,R.J., Alewood,P.F., Vetter,I. and Dutertre,S. (2015) δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proc. Biol. Sci. 282

Internal links

Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Wednesday 27 September 2023