Con-ins G1 A chain (P06935) Protein Card

General Information
Name Con-ins G1 A chain (named by ConoServer)
Organism Conus geographus (Geography cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Wild type
Protein precursor Con-ins G1 precursor (6870)
Notes C7 and C20 form disulfide bridges with B chain (P06934).

Conopeptide class coninsulin
Gene superfamily Insulin superfamily
Pharmacological family

Modified residues
4GlaGamma carboxylic glutamic acid
15GlaGamma carboxylic glutamic acid
21nh2C-term amidation
Sequence evidence protein level
Average Mass 2397.70
Monoisotopic Mass 2395.99
Isoelectric Point 8.16
Extinction Coefficient [280nm] 1990.00

Synthetic variants
Con-ins G1 A Chain[C6U,C11U] GVVEH(Sec)CHRP(Sec)SNAEFKKYCG

Safavi-Hemami,H., Gajewiak,J., Karanth,S., Robinson,S.D., Ueberheide,B., Douglass,A.D., Schlegel,A., Imperial,J.S., Watkins,M., Bandyopadhyay,P.K., Yandell,M., Li,Q., Purcell,A.W., Norton,R.S., Ellgaard,L. and Olivera,B.M. (2015) Specialized insulin is used for chemical warfare by fish-hunting cone snails. Proc. Natl. Acad. Sci. U.S.A. 112:1743-1748

Internal links
Protein Precursor Con-ins G1 precursor (6870)
Nucleic acids
Structure Structure of Conus Geographus insulin G1

External links