Am6.1 (P07473) Protein Card

General Information

Name	Am6.1
Alternative name(s)	Am3452
Organism	Conus amadis
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Wild type
Protein precursor	Am6.1 precursor (9039)
Notes	Vijayasarathy et al., 2018 reported that unmodified and partial modified sequences were also detected in venom.

Classification

Conopeptide class	conotoxin
Gene superfamily	O2 superfamily
Cysteine framework	VI/VII
Pharmacological family

Sequence

CDG(Btr)STYCHDDS(Gla)CST(Gla)ANSYCTLIKGV
Modified residues	position symbol name 4 Btr Bromotryptophan 13 Gla Gamma carboxylic glutamic acid 17 Gla Gamma carboxylic glutamic acid
Sequence evidence	protein level
Average Mass	3251.18
Monoisotopic Mass	3248.06
Isoelectric Point	4.77
Extinction Coefficient [280nm]	2980.00

References

Vijayasarathy,M. and Balaram,P (2018) Mass spectrometric identification of bromotryptophan containing conotoxin sequences from the venom of C. amadis Toxicon 144:68-74

Internal links

Protein Precursor	Am6.1 precursor (9039)
Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Friday 1 December 2023