Lt1.3 [F15A] (P07494) Protein Card

General Information
Name Lt1.3 [F15A]
Organism synthetic construct
Protein Type Synthetic
Parent Lt1.3 [globular]

Classification
Conopeptide class conotoxin
Gene superfamily
Cysteine framework I
Pharmacological family alpha conotoxin

Sequence
GCCSHPACSGNNPYAC(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Sequence evidence protein level
Average Mass 1578.72
Monoisotopic Mass 1577.53
Isoelectric Point 8.42
Extinction Coefficient [280nm] 1490.00

Activity

IC50: Nicotinic acetylcholine receptors

TargetOrganismIC50nhillAgonistRef
α3β2R. norvegicus>10uM4100uM AchChen J et al. (2018)

References
Chen J, Liang L, Ning H, Cai F, Liu Z, Zhang L, Zhou L, Dai Q (2018) Cloning, Synthesis and Functional Characterization of a Novel α-Conotoxin Lt1.3 Marine drugs 16:112

Internal links
Nucleic acids
Structure

External links

Tools