SI precursor (P00076) Protein Card

General Information
Name SI precursor
Organism Conus striatus (Striated cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily A superfamily
Pharmacological family

Sequence
MGMRMMFTVFLLVVLATTVVS
FPSDRASDGRDDEAKDERSD
MHESDRKE
ICCNPACGPKYSC
GR
Sequence region
[1-21]signal sequence
[50-62]mature peptideSI

References
Benie,A.J., Whitford,D., Hargittai,B., Barany,G. and Janes,R.W. (2000) Solution structure of alpha-conotoxin SI FEBS Lett. 476:287-295
Santos,A.D., McIntosh,J.M., Hillyard,D.R., Cruz,L.J. and Olivera,B.M. (2004) The A-superfamily of conotoxins: structural and functional divergence J. Biol. Chem. 279:17596-17606
Lu,B.S., Yu,F., Zhao,D., Huang,P.T. and Huang,C.F. (1999) Conopeptides from Conus striatus and Conus textile by cDNA cloning Peptides 20:1139-1144
Zafaralla,G.C., Ramilo,C., Gray,W.R., Karlstrom,R., Olivera,B.M. and Cruz,L.J. (1988) Phylogenetic specificity of cholinergic ligands: alpha-conotoxin SI Biochemistry 27:7102-7105

Internal links
Nucleic acids Sequence 30 from patent US 6855805
Alpha Conotoxin Peptides
Structure

External links
UniProtKB/Swiss-Prot P15471
Ncbi P15471

Tools