MVIIC precursor (P00822) Protein Card

General Information
Name MVIIC precursor
Organism Conus magus (Magus cone)
Organism region Indo-Pacific
Organism diet piscivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily
Pharmacological family

Sequence
TR
CKGKGAPCRKTMYDCCSGSCGRRGKC
G
Sequence region
[3-28]mature peptideMVIIC

References
Hillyard,D.R., Monje,V.D., Mintz,I.M., Bean,B.P., Nadasdi,L., Ramachandran,J., Miljanich,G., Azimi-Zoonooz,A., McIntosh,J.M., Cruz,L.J. et al. (1992) A new Conus peptide ligand for mammalian presynaptic Ca2+ channels Neuron 9:69-77
Farr-Jones,S., Miljanich,G.P., Nadasdi,L., Ramachandran,J. and Basus,V.J. (1995) Solution structure of omega-conotoxin MVIIC, a high affinity ligand of P-type calcium channels, using 1H NMR spectroscopy and complete relaxation matrix analysis J. Mol. Biol. 248:106-124
Nielsen,K.J., Adams,D., Thomas,L., Bond,T., Alewood,P.F., Craik,D.J. and Lewis,R.J. (1999) Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels J. Mol. Biol. 289:1405-1421
Kim,J.I., Takahashi,M., Martin-Moutot,N., Seagar,M.J., Ohtake,A. and Sato,K. (1995) Tyr13 is essential for the binding of omega-conotoxin MVIIC to the P/Q-type calcium channel Biochem. Biophys. Res. Commun. 214:305-309

Internal links
Nucleic acids omega-CgTx-MVIIC=omega-conotoxin [Conus magus, venom ducts, mRNA Partial, 90 nt]
Structure

External links
UniProtKB/Swiss-Prot P37300
Ncbi P37300, AAB22674

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