Mr5.4a precursor (P00859) Protein Card

General Information

Name	Mr5.4a precursor
Alternative name(s)	Mr074
Organism	Conus marmoreus
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Precursor

Classification

Conopeptide class	conotoxin
Gene superfamily	T superfamily
Pharmacological family

Sequence

MRCVPVFVILLLLIASAPS VDVQLKTKDDVPLASFHANVKR TLQILLNKR CCQVMPQCCEWN
Sequence region	[1-19] signal sequence [51-62] mature peptide Mr5.4a

References

Han,Y.H., Wang,Q., Jiang,H., Miao,X.W., Chen,J.S. and Chi,C.W. (2005) Sequence diversity of T-superfamily conotoxins from Conus marmoreus Toxicon 45:481-487

Dutertre,S., Jin,A.H., Kaas,Q., Jones,A., Alewood,P.F. and Lewis,R.J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol. Cell Proteomics 12:312-329

Internal links

Nucleic acids	Conus marmoreus tau conotoxin 5.4a mRNA, complete cds
Structure

External links

UniProtKB/Swiss-Prot	Q6PN82
Ncbi	Q6PN82, AAT01632

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Thursday 1 June 2023