TxIB[insN_GGAAG] cyclic (P08899) Protein Card

General Information
Name TxIB[insN_GGAAG] cyclic (named by ConoServer)
Alternative name(s) cTxIB-5
Organism synthetic construct
Protein Type Synthetic
Parent TxIB

Classification
Conopeptide class conotoxin
Gene superfamily
Pharmacological family

Sequence
GGAAGGCCSDPPCRNKHPDLC
Sequence evidence protein level
Average Mass 2054.27
Monoisotopic Mass 2052.80
Isoelectric Point 8.31
Extinction Coefficient [280nm] NA

Activity

Percentage inhibition: Nicotinic acetylcholine receptors

TargetOrganism% inhibitionConcentrationAgonistRef
α6β2β3R. norvegicus42100 nMAch (100 uM)Li,X. et al. (2020)

References
Li,X., Wang,S., Zhu,X., Zhangsun,D., Wu,Y. and Luo,S (2020) Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB Mar Drugs 18

Internal links
Nucleic acids
Structure

External links

Tools