AtVIA[I25L,V28L,T30S] (P09001) Protein Card

General Information

Name	AtVIA[I25L,V28L,T30S]
Organism	synthetic construct
Protein Type	Synthetic
Parent	AtVIA
Notes	Neves et al.,2019 reported that AtVIA[I25L,V28L,T30S] showed the same excitatory activity on mouse lumbar dorsal root ganglion neurons as AtVIA.

Classification

Conopeptide class	conotoxin
Gene superfamily
Cysteine framework	VI/VII
Pharmacological family

Sequence

ZCGADGQFCFLPGLGLNCCSGLCLLVCLPS
Modified residues	position symbol name 1 Z Pyroglutamic acid
Sequence evidence	protein level
Average Mass	NA
Monoisotopic Mass	NA
Isoelectric Point	1.04
Extinction Coefficient [280nm]	NA

References

Neves,J.L.B., Imperial,J.S., Morgenstern,D., Ueberheide,B., Gajewiak,J., Antunes,A., Robinson,S.D., Espino,S., Watkins,M., Vasconcelos,V. and Olivera,B.M. (2019) Characterization of the First Conotoxin from Conus ateralbus, a Vermivorous Cone Snail from the Cabo Verde Archipelago Mar Drugs 17:432

Internal links

Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Monday 20 March 2023