SII precursor (P00091) Protein Card

General Information

Name	SII precursor
Organism	Conus striatus (Striated cone)
Organism region	Indo-Pacific
Organism diet	piscivorous
Protein Type	Precursor

Classification

Conopeptide class	conotoxin
Gene superfamily	A superfamily
Pharmacological family

Sequence

MGMRMMFTVFLLVVLATTVVSFPS DRASDGRDDEAKDERSD MHESDRNGR GCCCNPACGPNYGCGTSCS RTI
Sequence region	[1-24] signal sequence [51-69] mature peptide SII

References

Wang,C.Z., Jiang,H., Ou,Z.L., Chen,J.S. and Chi,C.W. (2003) cDNA cloning of two A-superfamily conotoxins from Conus striatus Toxicon 42:613-619

Ramilo,C., Zafaralla,G.C., Nadasdi,L., Hammerland,L.G., Yoshikami,D., Gray,W.R., Kristipati,R., Ramachandran,J., Miljanich,G.P., Olivera,B.M. and Cruz,L.J. (1992) Novel alpha- and omega-conotoxins from Conus striatus venom Biochemistry 31:9919-9926

Wang,C.Z., Ou,Z.L. and Chi,C.W. (2004) Gene cloning and functional studies of alpha conotoxin SII

Internal links

Nucleic acids	Conus striatus alpha conotoxin SII precursor, mRNA, complete cds Conus striatus A superfamily conotoxin SII precursor, gene, complete cds.
Structure

External links

UniProtKB/Swiss-Prot	P28879
Ncbi	AAN77902

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 5 December 2023