Conorfamide-Ep1 (P09977) Protein Card

General Information

Name	Conorfamide-Ep1 (named by ConoServer)
Alternative name(s)	CNF-Ep1
Organism	Conus episcopatus
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Synthetic
Protein precursor	Conorfamide-Ep1 precursor (9978)
Notes	This peptide induced alterations in the locomotor behavior of zebrafish larvae (Bosse et al. 2021).

Classification

Conopeptide class	conorfamide
Gene superfamily
Pharmacological family

Sequence

NFGILFYFTRPRNNFVRI(nh2)
Modified residues	position symbol name 19 nh2 C-term amidation
Sequence evidence	nucleic acid level
Average Mass	2273.68
Monoisotopic Mass	2272.24
Isoelectric Point	12.80
Extinction Coefficient [280nm]	1490.00

References

Bosse,G.D., Urcino,C., Watkins,M., Flórez Salcedo,P., Kozel,S., Chase,K., Cabang,A., Espino,S.S., Safavi-Hemami,H., Raghuraman,S., Olivera,B.M., Peterson,R.T. and Gajewiak,J. (2021) Discovery of a Potent Conorfamide from Conus episcopatus Using a Novel Zebrafish Larvae Assay. J Nat Prod

Internal links

Protein Precursor	Conorfamide-Ep1 precursor (9978)
Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Wednesday 22 March 2023